I-PBMT iwukwelashwa ngokukhanya kwe-laser noma kwe-LED okuthuthukisa ukulungiswa kwezicubu (amanxeba esikhumba, imisipha, imisipha, amathambo, imizwa), kunciphisa ukuvuvukala futhi kunciphisa ubuhlungu noma kuphi lapho kufakwa khona umsebe.
Kutholakale ukuthi i-PBMT isheshisa ukululama, inciphise ukulimala kwemisipha futhi inciphise ubuhlungu ngemva kokuzilolonga.
Ngesikhathi se-Space Shuttle, i-NASA yayifuna ukufunda ukuthi izitshalo zikhula kanjani emkhathini. Kodwa-ke, imithombo yokukhanya esetshenziselwa ukutshala izitshalo eMhlabeni yayingafanelani nezidingo zazo; yayisebenzisa amandla amaningi kakhulu futhi yadala ukushisa okukhulu.
Ngawo-1990, iWisconsin Center for Space Automation & Robotics yabambisana neQuantum Devices Inc. ukuthuthukisa umthombo wokukhanya osebenzayo kakhudlwana. Basebenzise ama-diode akhipha ukukhanya (ama-LED) ekusungulweni kwabo, i-Astroculture3. I-Astroculture3 iyigumbi lokukhulisa izitshalo, elisebenzisa izibani ze-LED, ezisetshenziswe yi-NASA ngempumelelo emisebenzini eminingana ye-Space Shuttle.
Ngokushesha, i-NASA yathola ukusetshenziswa okungenzeka kokukhanya kwe-LED hhayi nje kuphela empilweni yezitshalo, kodwa nakubantu abasebenzisa izinkanyezi ngokwabo. Njengoba behlala endaweni ephansi yamandla adonsela phansi, amangqamuzana abantu awavuseleli ngokushesha, futhi abenzi bezinkanyezi babhekana nokulahlekelwa amathambo nemisipha. Ngakho-ke i-NASA yaphendukela ekwelashweni nge-photobiomodulation (PBMT). Ukwelashwa nge-photobiomodulation kuchazwa njengohlobo lokwelashwa kokukhanya olusebenzisa imithombo yokukhanya engeyona i-ionizing, kufaka phakathi ama-laser, ama-diode akhipha ukukhanya, kanye/noma ukukhanya kwe-broadband, ku-spectrum ye-electromagnetic ebonakalayo (400 - 700 nm) kanye ne-near-infrared (700 - 1100 nm). Kuyinqubo engashisi ehilela ama-chromophores emvelo abangela izenzakalo ze-photophysical (okungukuthi, eziqondile nezingezona eziqondile) kanye ne-photochemical ezikalini ezahlukene zebhayoloji. Le nqubo iphumela emiphumeleni yokwelapha enenzuzo efaka phakathi kodwa ingagcini ekunciphiseni ubuhlungu, ukuguquguquka kwamasosha omzimba, kanye nokukhuthaza ukuphulukiswa kwamanxeba nokuvuselelwa kwezicubu. Igama elithi ukwelashwa nge-photobiomodulation (PBM) manje lisetshenziswa abacwaningi nodokotela esikhundleni samagama anjenge-low level laser therapy (LLLT), i-cold laser, noma i-laser therapy.
Amadivayisi okwelapha ngokukhanya asebenzisa izinhlobo ezahlukene zokukhanya, kusukela ekukhanyeni okungabonakali, okuseduze kwe-infrared ngokusebenzisa i-spectrum yokukhanya okubonakalayo (obomvu, o-orenji, ophuzi, oluhlaza okotshani, nohlaza okwesibhakabhaka), okuma ngaphambi kwemisebe ye-ultraviolet eyingozi. Kuze kube manje, imiphumela yokukhanya okubomvu nokuseduze kwe-infrared yiyo efundwa kakhulu; ukukhanya okubomvu kuvame ukusetshenziselwa ukwelapha izimo zesikhumba, kuyilapho i-infrared eseduze ingangena ngokujulile kakhulu, isebenze esikhumbeni nasemathanjeni ngisho nasebuchosheni. Ukukhanya okuluhlaza kucatshangwa ukuthi kuhle kakhulu ekwelapheni izifo futhi kuvame ukusetshenziselwa induna. Imiphumela yokukhanya okuluhlaza nokuphuzi ayiqondwa kahle, kodwa okuluhlaza kungathuthukisa i-hyperpigmentation, kanti okuphuzi kunganciphisa i-photoaging.
