Ukwelashwa nge-laser kuwukwelapha okusebenzisa ukukhanya okugxilile ukuze kushukumise inqubo ebizwa ngokuthi i-photobiomodulation (i-PBM isho ukuthi i-photobiomodulation). Ngesikhathi se-PBM, ama-photon angena kusishu futhi ahlanganyele ne-cytochrome c complex ngaphakathi kwe-mitochondria. Lokhu kusebenzisana kubangela izigameko zebhayoloji eziholela ekwandeni kwe-metabolism yamangqamuzana, okunganciphisa ubuhlungu kanye nokusheshisa inqubo yokuphulukisa.
I-Photobiomodulation therapy ichazwa njengohlobo lokwelapha olukhanyayo olusebenzisa imithombo yokukhanya enga-ionizing, okuhlanganisa amalaser, ama-diode akhipha ukukhanya, kanye/noma ukukhanya kwe-broadband, kokubonakalayo (400 – 700 nm) kanye ne-infrared eseduze (700 – 1100 nm) i-electromagnetic spectrum. Kuyinqubo engashisi ukushisa ehilela ama-chromophore e-endogenous evuselela i-photophysical (okungukuthi, eqondile kanye ne-nonlinear) kanye nemicimbi ye-photochemical esikalini sebhayoloji ehlukahlukene. Le nqubo iholela emiphumeleni yokwelapha enenzuzo ehlanganisa kodwa engagcini nje ekunciphiseni ubuhlungu, i-immunomodulation, kanye nokukhuthazwa kokuphulukiswa kwesilonda nokuvuselelwa kwezicubu. Itemu elithi photobiomodulation (PBM) therapy manje selisetshenziswa abacwaningi nodokotela esikhundleni samagama afana neleveli yokwelapha nge-laser (LLLT), i-cold laser, noma i-laser therapy.
Izimiso eziyisisekelo ezisekela ukwelashwa kwe-photobiomodulation (PBM), njengoba kuqondwa njengamanje ezincwadini zesayensi, ziqondile. Kukhona ukuvumelana ukuthi ukusetshenziswa komthamo wokwelapha wokukhanya kuzicubu ezikhubazekile noma ezingasebenzi kuholela ekuphenduleni kweselula okuqondiswa yizinqubo ze-mitochondrial. Ucwaningo luye lwabonisa ukuthi lezi zinguquko zingathinta ubuhlungu nokuvuvukala, kanye nokulungiswa kwezicubu.