Ukwelashwa nge-laser kuyindlela yokwelapha esebenzisa ukukhanya okugxilile ukuvuselela inqubo ebizwa ngokuthi i-photobiomodulation (i-PBM isho i-photobiomodulation). Ngesikhathi se-PBM, ama-photon angena ezicutshini futhi asebenzisane ne-cytochrome c complex ngaphakathi kwe-mitochondria. Lokhu kusebenzisana kubangela uchungechunge lwezinto eziphilayo lwezehlakalo eziholela ekwandeni kwe-metabolism yamaseli, okunganciphisa ubuhlungu kanye nokusheshisa inqubo yokuphulukiswa.
Ukwelashwa nge-Photobiomodulation kuchazwa njengohlobo lokwelashwa kokukhanya olusebenzisa imithombo yokukhanya engeyona i-ionizing, kufaka phakathi ama-laser, ama-diode akhipha ukukhanya, kanye/noma ukukhanya kwe-broadband, ku-spectrum ye-electromagnetic ebonakalayo (400 - 700 nm) kanye ne-near-infrared (700 - 1100 nm). Kuyinqubo engashisi ehilela ama-chromophores e-endogenous akhipha izenzakalo ze-photophysical (okungukuthi, eziqondile nezingezona eziqondile) kanye ne-photochemical ezikalini ezahlukene zebhayoloji. Le nqubo iphumela emiphumeleni yokwelapha enenzuzo efaka phakathi kodwa kungagcini ekunciphiseni ubuhlungu, ukuguquguquka kwamasosha omzimba, kanye nokukhuthaza ukuphulukiswa kwamanxeba kanye nokuvuselelwa kwezicubu. Igama elithi ukwelashwa nge-photobiomodulation (PBM) manje lisetshenziswa abacwaningi nodokotela esikhundleni samagama anjenge-low level laser therapy (LLLT), i-cold laser, noma i-laser therapy.
Izimiso eziyisisekelo ezisekela ukwelashwa nge-photobiomodulation (PBM), njengoba kuqondwa njengamanje ezincwadini zesayensi, zilula kakhulu. Kukhona ukuvumelana ngokuthi ukusetshenziswa komthamo wokwelapha wokukhanya ezicutshini ezikhubazekile noma ezingasebenzi kahle kuholela empendulweni yamaseli eqondiswa izindlela ze-mitochondrial. Izifundo zikhombisile ukuthi lezi zinguquko zingathinta ubuhlungu nokuvuvukala, kanye nokulungiswa kwezicubu.